A further LINK

Further thoughts on the aluminum-Alzheimer's disease link.

UNLABELLED STUDY OBJECTIVE AND METHOD: The results of studies on aluminum (Al) and Alzheimer's disease (AD) from groups in Newcastle, UK and Ontario, Canada were compared in order to explain why the former were unable to detect a link while the latter could, and to suggest alternative ways of examining the data. RESULTS The Al concentrations in the Newcastle study were relatively small compar...

A Further Note on Runs in Independent Sequences

Given a sequence of letters generated independently from a finite alphabet, we consider the case when more than one, but not all, letters are generated with the highest probability. The length of the longest run of any of these letters is shown to be one greater than the length of the longest run in a particular state of an associated Markov chain. Using results of Foulser and Karlin (19...

Hirschsprung's disease associated with a deletion of chromosome 10 (q11.2q21.2): a further link with the neurocristopathies?

We report a patient with total colonic aganglionosis in association with a deletion of part of the long arm of chromosome 10: (del(10)(q11.2q21.2)). This deletion includes the ret proto-oncogene, which has recently been implicated in multiple endocrine neoplasia type 2A (MEN 2A). The possible links between Hirschsprung's disease and the neurocristopathies and the aetiological role of abnormalit...

Resistant Hypertension, Elevated Aldosterone/Renin Ratio and Reduced RGS2: A Pathogenetic Link Deserving Further Investigations?

Difficulty distinguishing benign notochordal cell tumor from chordoma further suggests a link between them

BACKGROUND Much discussion about benign notochordal cell tissue in vertebrae has centered on the nature of its relationship, if any, to chordoma. Often referred to as benign notochordal cell tumors (BNCTs), these lesions have unique morphological features, however, differentiating between notochordal cells in discs, BNCT, and chordoma can be difficult. They are described as radiologically disti...